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Description

Nissen expects tirzepatide to soon join the pure GLP-1 RAs with an FDA-approved indication for weight loss in addition to diabetes, although it may meet the same payer reluctance around reimbursement for weight loss that the pure GLP-1 RAs have

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5,19 Like any medication, GLP-1RAs may have side effects, including nausea, vomiting, diarrhea, and injection site reactions

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This lack of lifestyle integration not only blunts weight loss (since diet/exercise contribute significantly), but also magnifies attrition patients who arent seeing lifestyle progress or feel unsupported are more likely to give up on the medication when challenges arise

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